Lichenoid Dermatitis with Eosinophils Treatment

Lichenoid Dermatitis

Lichenoid dermatitis is an inflammatory dermatological condition that results in damage to the mucous membranes and inner layers of skin tissues such as dermis, and hair follicles. The disease takes its name from the appearance of the scaly rash that resembles lichens according to WebMD. Out of all the types of dermatitis this can be one of the most difficult to treat, and one of the most serious. This condition may also be referred to as lichen planus, and raised bumps which have a purple coloring are usually the best way to identify this condition. This type of rash could affect scalp of the head, back, arms, nails and legs.

Lichenoid dermatitis takes on so many different forms making the correct diagnosis a matter of time. Most of the time doctors witness round shaped clusters of rash, purple blistery rash and ulcers on the feet and shins. Lichenoid dermatitis can also be classified under another condition in the mucous membranes of the mouth, called lichen mucositis, which causes lesions, blisters, and ulcers to appear that are a whitish color.

Contact dermatitis symptoms may also appear with a lichen planus rash, because this rash is also an allergic reaction to contact with a chemical or other substances like medications. Medications that treat high blood pressure, arthritis and low blood sugar are the most common culprits to developing this autoimmune dermatological response. An underlying medical condition or disease may also cause lichenoid dermatitis to appear. Allergies cause an increase in eosinophils in the blood to increase, and this may be partly responsible for the response of the body. This is also true with dyshidrotic dermatitis and other types of conditions caused by allergic reactions. Your immune system releases substances to combat any threats, however the response of the body is the biggest threat with allergies.

While the causes of lechenoid dermatitis can almost always be identified, finding the right treatment is a challenging task. There’s no cure for this condition: removing the triggers and providing symptom relief are one of the basic approaches to addressing lichenoid dermatitis. Treating lichenoid dermatitis can involve antihistamines and creams which contain steroids, to minimize the rash and itching. This is usually the same treatment for neurodermatitis and other skin rashes as well. Many cases will disappear within one year without any treatment, but others may become more serious. For severe cases a steroid oral medication may be prescribed.

In extreme cases a new treatment that involves lowering the number of eosinophils in the blood stream may also be tried. Eosinophils are white blood cells and integral components of the immune system responsible for fighting off viruses and bacteria. These cells also play a significant role in the treatment of allergies and asthma. Since lichenoid dermatitis is considered an autoimmune disorder, this innovative treatment focuses on lowering the number of these cells in blood. This is done by injecting a human interleukin-5 antagonist through an IV into the blood, where these compounds will fight off excessive levels of eosinophils in the body. This treatment is fairly new, and does have risks, so it is only done in very serious cases.